The role of positron emission tomography/computed tomography in the diagnosis of pleural diseases
Thoracic and Cardiovascular Surgeon, cilt.57, sa.4, ss.217-221, 2009 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 57 Sayı: 4
- Basım Tarihi: 2009
- Doi Numarası: 10.1055/s-2008-1039314
- Dergi Adı: Thoracic and Cardiovascular Surgeon
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.217-221
- Anahtar Kelimeler: PET/CT, Pleural diseases, VATS
- Maltepe Üniversitesi Adresli: Evet
Özet
Background: The aim of the study was to assess the role of F-18 fluoro-2-D-deoxyglucose positron emission tomography (18FDG-PET)/ computed tomography (CT) in patients with undiagnosed pleural diseases and to compare the findings with those of invasive diagnostic procedures. Methods: The study included 83 patients with pleural lesions (63 with pleural effusion; 20 with pleural thickening) on CT scan performed between November 2005 and December 2007. The study group consisted of 63 males and 20 females; their median age was 47 years, PET-CT scan was performed for all patients before surgery. A maximum standard uptake value greater than 3.0 was accepted as positive for malignancy. For histopathological diagnosis, video-assisted thoracoscopic surgery was performed in 76 patients and a mini-thoracotomy was performed for the remaining 7 patients. Results: Postoperative histopathological examination revealed malignancy in 44 cases, 25 of which were malignant mesothelioma; the remaining 39 cases were benign. There were no false negative results, but two false positive results (tuberculosis), PET-CT scanning had 100% sensitivity, 94.8% specificity and 97.5% accuracy, Conclusion: Our study suggests that PET-CT may be an effective tool for the differentiation of benign and malignant pleural diseases, We believe that PET/CT may prevent redundant surgical procedures in young patients who are SUVmax negative. © Georg Thieme Verlag KG Stuttgart, New York.