Comparison of serum androgens and endometrial thickness in obese and non-obese postmenopausal women Obez ve obez olmayan postmenopozal hastalarda serum androjen seviyeleri ve endometrial kalınlıǧn karşılaştınlması
Journal of the Turkish German Gynecology Association, cilt.11, sa.3, ss.149-151, 2010 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 11 Sayı: 3
- Basım Tarihi: 2010
- Doi Numarası: 10.5152/jtgga.2010.23
- Dergi Adı: Journal of the Turkish German Gynecology Association
- Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.149-151
- Anahtar Kelimeler: Endometrial thickness, Obesity, Postmenopause, Serum androgene
- Maltepe Üniversitesi Adresli: Evet
Özet
Objective: In this study, we investigated whether serum androgen levels and endometrial thickness differed in obese and non-obese women. Material and Methods: Thirtytwo non-obese (BMI <30) and 48 obese (BMI ≥ 30) women were enrolled. Blood samples were analyzed for testosterone, free testosterone, androstenedione, DHEAS, and SHBG, and transvaginal ultrasonography was performed. Results: Obese women had significantly higher free testosterone and endometrial thickness and significantly lower SHBG. Eight of 17 women with endometrial thickness >5 mm had significant pathology. Conclusion: These results suggest that obesity may be a risk factor for endometrial carcinoma and other pathologies in post-menopausal women through an action on androgen concentrations.