Quantitative analysis of subfoveal choroidal thickness using enhanced depth imaging optical coherence tomography in normal eyes

Ozdogan Erkul S., Kapran Z., Uyar O. M.

International Ophthalmology, cilt.34, sa.1, ss.35-40, 2014 (Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 34 Sayı: 1
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1007/s10792-013-9787-6
  • Dergi Adı: International Ophthalmology
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.35-40
  • Anahtar Kelimeler: Choroidal thickness, Enhanced depth imaging, Optic coherence tomography
  • Maltepe Üniversitesi Adresli: Evet

Özet

To evaluate subfoveal choroidal thickness of normal eyes with the use of the enhanced depth imaging technique of optical coherence tomography (EDI-OCT) and correlation of choroidal thickness with patient age. A retrospective analysis of 123 healthy eyes was performed. Age, gender, refractive state and spheric equivalencies were noted. Subfoveal choroidal thickness was measured and noted manually by two independent observers. A total of 72 patients (123 eyes) were included in this study. The mean age of the patients was 47.47 (15-84). The mean spheric equivalent of the refractive error was -0.24 D. According to LogMAR, the mean visual acuity was -0.006. The mean subfoveal choroidal thickness was 280.23 μm (SD ± 81.15, range 124-527 μm). The choroidal thickness showed a negative correlation with age for the subfoveal location (p = 0.000a). Regression analysis showed that subfoveal choroidal thickness decreased 3.14 μm for each year of age. The regression formulation was choroidal thickness = 429 - 3.14 × age. When we compared eyes according to their spheric equivalencies, there was no statistically significant correlation between spheric equivalency and subfoveal choroidal thickness. (p = 0.14). In this study, we report choroidal thickness measurement among healthy eyes within the Turkish population to demonstrate that EDI-OCT imaging can give cross-sectional information regarding the choroid, thereby facilitating quantitative imaging. © 2013 Springer Science+Business Media.