Role of 18F-FDG PET/CT imaging in the strategic selection of the accessory spleen as a biopsy site for definitive lymphoma diagnosis in a 67-year-old man: A Case report Rôle de l’imagerie TEP/TDM au 18F-FDG dans la sélection stratégique de la rate accessoire comme site de biopsie pour le diagnostic définitif du lymphome chez un homme de 67 ans : rapport de cas
Medecine Nucleaire, cilt.50, sa.3, ss.111-113, 2026 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 50 Sayı: 3
- Basım Tarihi: 2026
- Doi Numarası: 10.1016/j.mednuc.2025.09.010
- Dergi Adı: Medecine Nucleaire
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE
- Sayfa Sayıları: ss.111-113
- Anahtar Kelimeler: 18F-FDG, Accessory spleen, Case report, Hematology, Lymphoma, Non-invasive diagnosis, Nuclear medicine, Oncology, PET/CT, Splenic involvement
- Maltepe Üniversitesi Adresli: Evet
Özet
The role of 18F-FDG PET/CT in lymphoma staging and treatment response assessment is well established in the literature. Beyond these conventional applications, it can also serve as a powerful tool for guiding biopsy decisions in diagnostically challenging cases. We present the case of a 67-year-old man with suspected lymphoma, in whom initial diagnostic procedures—including bone marrow aspiration—failed to yield conclusive results. A multidisciplinary team utilized 18F-FDG PET/CT to identify an accessory spleen exhibiting metabolic activity comparable to the primary spleen. Given its accessibility and diagnostic potential, the accessory spleen was surgically excised, leading to a definitive diagnosis of mantle cell lymphoma. This case underscores the strategic role of PET/CT in biopsy site selection, offering a safer and less invasive diagnostic alternative and reinforcing its crucial role in lymphoma management.