Combination of hypoosmotic swelling/eosin Y test for sperm membrane integrity evaluation: Correlations with other sperm parameters to predict ICSI cycles
Archives of Andrology, cilt.53, sa.1, ss.25-28, 2007 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 53 Sayı: 1
- Basım Tarihi: 2007
- Doi Numarası: 10.1080/01485010600888912
- Dergi Adı: Archives of Andrology
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.25-28
- Anahtar Kelimeler: Eosin Y exclusion test, Hypoosmotic swelling test, ICSI outcome, Sperm membrane integrity
- Maltepe Üniversitesi Adresli: Evet
Özet
The objective of our study was to evaluate the accuracy of the combination of hypoosmotic swelling (HOS) and eosin Y (Ey) exclusion tests to predict the ICSI cycles' outcome and its correlations with other sperm parameters. The functional and structural integrity of sperm membrane was evaluated with the combined HOS/Ey test in 95 ICSI cycles and the results were correlated with other sperm parameters, including concentration, motility, strict morphology, and total motile sperm count. The combined HOS/Ey test was evaluated for the prediction of the ICSI cycles' outcome parameters including fertilization, cleavage, and pregnancy rates. The HOS/Ey test presented significant relationships with concentration, motility, and strict morphology (p < 0,0001) but it couldn't predict the fertilization, cleavage, and pregnancy outcomes of ICSI cycles. The combined HOS/Ey test has strong correlations with motility and strict morphology parameters of sperm samples but is not sufficiently sensitive to estimate the outcome of ICSI cycles. Copyright © Informa Healthcare.