Comparison of Live Birth Rates Between Frozen-Thawed and Fresh Blastocyst Transfer for Male Infertility Comparación de las tasas de nacidos vivos entre la transferencia de blastocitos congelados y frescos para la infertilidad masculina
Revista Peruana de Ginecologia y Obstetricia, cilt.70, sa.4, 2024 (ESCI, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 70 Sayı: 4
- Basım Tarihi: 2024
- Doi Numarası: 10.31403/rpgo.v70i2686
- Dergi Adı: Revista Peruana de Ginecologia y Obstetricia
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, DIALNET
- Anahtar Kelimeler: Embryo Transfer, Fertilization in vitro, Live birth, Pregnancy rate, Vitrification
- Maltepe Üniversitesi Adresli: Evet
Özet
Background: In recent years, with the development of assisted reproductive techniques, different in vitro fertilization-embryo transfer protocols have been developed. Embryo cryopreservation has emerged as an alternative to fresh embryo transfer. The superiority of fresh versus frozen-thawed embryo transfer in terms of pregnancy outcome varies among studies. Objective: To compare pregnancy and live birth rates resulting from fresh and frozen-thawed blastocyst transfers in male infertile couples. Methods: In this retrospective study, 803 intracytoplasmic sperm injection-embryo transfer cycles (304 fresh and 499 frozen-thawed) from 2019 to 2022 were reviewed. The results of pregnancy rates were compared as a function of embryo transfer method. In addition, pregnancy rates were evaluated as a function of embryo transfer method and maternal age. Results: The mean age of women in the fresh and frozen-thawed blastocyst transfer groups and the proportion of fresh and frozen-thawed transfers in the age groups were similar. Pregnancy rates of all cases differed between the two groups, with higher rates observed in the group that underwent fresh blastocyst transfer. However, live birth rates were similar. In addition, when pregnancy rates were compared according to maternal age, no significant differences were found. In all cases and fresh blastocyst transfer, pregnancy rates decreased with increasing age. Conclusion: Our results indicate comparable live birth rates with fresh embryo transfer compared to frozen-thawed transfers in male factor infertility.